Protein Purification Reagents and Kits
Cell Signaling Technology SimpleChIP Human CDKN1A Promoter Primers 500 µl
SimpleChIP Human CDKN1A Promoter Primers 500 µl
Genscript Corporation Nectin-2/CD112Biotin His
Nectin-2 is an adhesion molecule that has been reported to play a role in tumor growth metastasis and tumor angiogenesis Nectin-2 expression in ovarian cancer may support tumor cell adhesion leading to growth and lymph node metastasis Effect of VEGF on Nectin-2 expression as well as permeability was investigated in HUVEC
AdipoGen CD152 hrecHis
Recombinant Protein. Human CD152 aa 36-161 is fused at the C-terminus to a His-tag. Source W2. Lyophilized. Contains PBS. CD152 Cytotoxic T-lymphocyte-associated protein 4 CTLA-4 is an inhibitory receptor belonging to the CD28 immunoglobulin subfamily, expressed primarily by T-cells. Its ligands, CD80 and CD86, are typically found on the surface of antigen-presenting cells and can either bind CD28 or CTLA-4, resulting in a costimulatory or a co-inhibitory response, respectively. Because of its dampening effect, CTLA-4 is a crucial regulator of T-cell homeostasis and self-tolerance. While CD28 promotes T-cell activation and proliferation, CTLA-4 is reported to dampen T-cell responses through a variety of mechanisms. Prior to activation, conventional T-cells Tconv express low levels of CTLA-4, predominantly in intracellular compartments. Upon activation, CTLA-4 expression is upregulated and becomes increasingly detectable on the cell surface.
AdipoGen Sortilin human rec His
Recombinant Protein. Human sortilin aa 78-755 is fused at the C-terminus to a His-tag. Source W2. Lyophilized. Contains PBS. Sortilin is a type I transmembrane multiligand receptor that is a member of the Vacuolar protein sorting 10 protein Vps10p domain receptor family. It is a 95 kDa protein, ubiquitously expressed, although most abundantly expressed in neurons, hepatocytes, adipocytes and white blood cells including macrophages. Sortilin is synthesized as a propeptide in the endoplasmic reticulum ER and processed to its mature form by furin-mediated cleavage in the trans-Golgi network. The primary function of sortilin is trafficking proteins from the Golgi to secretory vesicles and endolysosomal compartments. The majority of trafficking is from the Golgi to the endosomal compartment where sortilin deposits cargo targeted for catabolism in the lysosome and then is trafficked back to the Golgi via a retromer complex.
AdipoGen NMNAT2 human rec His
Protein. Human NMNA2 aa 2-307 is fused at the N-terminus to a His-tag. Source E. coli. Lyophilized in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl plus 0.025% CHAPS. Purity >90% SDS-PAGE. Nicotinamide mononucleotide adenylyltransferase 2 NMNAT2 catalyzes the formation of NAD from nicotinamide mononucleotide NMN and ATP. Can also use the deamidated form nicotinic acid mononucleotide NaMN as a substrate but with lower efficiency. NMNAT2 also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD. It is highly expressed in brain, in particular in cerebrum, cerebellum, occipital lobe, frontal lobe, temporal lobe and putamen. NMNAT2 is also found in the heart, skeletal muscle, pancreas and islets of Langerhans. NMNAT2 is essential for axon growth and survival. Its loss from injured axons may activate Wallerian degeneration axon degeneration induced by nerve injury, whereas NMNAT overexpression rescues axons from degeneration.
AdipoGen ACBP h rec His
Recombinant protein. Human acyl-CoA-binding protein aa 2-87 is fused at the C-terminus to a His-tag. Endotoxin <0.01EU/µg purified protein LAL test. Lyophilized. Contains PBS. Acyl-coenzyme A CoA-binding protein ACBP is an ubiquitously expressed 86 aa polypeptide that binds medium- and long-chain acyl-CoA esters with very high affinity. It plays a role as an intracellular carrier of acyl-CoA esters and regulates lipid metabolism in the cytoplasm of most cell types. In addition to its function within the cells as acyl-coenzyme A CoA-binding protein, ACBP also functions as secreted protein called Diazepam-Binding Inhibitor DBI that can interact with the benzodiazepine-binding site of the gamma-aminobutyric acid GABA type A receptor, GABAAR, and modulate its activity. ACBP is secreted upon induction of autophagy energy deficiency in different organisms including mouse and human. ACBP levels correlate with human body mass index BMI.
AdipoGen VEGF-C rat rec His
Protein. Rat VEGF-C 127aa is fused at the C-terminus to a His-tag. Source Sf9 cells. Lyophilized. Purity >90% SDS-PAGE. VEGF-C forms primarily non-covalently linked dimers. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. It binds and activates VEGFR-2 KDR/FLK1 and VEGFR-3 FLT4 receptors. It is a growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. It is involved in the regulation of the growth and/or differentiation of lymphatic endothelium. It is also a mitogen for vascular endothelial cells.
BIOHIPPO GITR-Puro-NFkB-RFP-Gluc LV
GITR-Puro-NFkB-RFP-Gluc is a transcription factor reporter lentiviral vector designed to monitor the target signaling pathway in living cells The construct carries a RFP fluorescent reporter under the control of pathway responsive elements and includes a puromycin selection marker to generate stable cell pools The lentivirus is provided as a ready to use VSV G pseudotyped preparation for efficient gene delivery and stable genomic integration Each vial provides a nominal titer of 5x10E6 transducing units TU Typical applications include pathway activation studies assay development compound screening and mechanism of action research The system is suitable for human and mouse cells and can be read using standard fluorescence microscopy flow cytometry or luciferase assays depending on the reporter gene This product is intended for research use only and is not for diagnostic or therapeutic procedures
Genscript Corporation CEACAM-6/CD66cBiotin His A
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) belongs to the human carcino-embryonic antigen (CEA) family Numerous lines of studies have indicated that altered expression of CEACAM6 may have a role in carcinogenesis and development
Dojindo Molecular Technologies Inc LYSOSOME STAINING DEEP RED 3/P
NC3841916 LYSOSOME STAINING DEEP RED 3/P
Abcam Proteasome Activity Assay Kit
Proteasome Activity Assay Kit
The product is subject to the following: Abcam Restricted Use Statement